Preheat oven to 350 degrees F. Line a large baking sheet ( or two smaller ones) with parchment paper.
Slice jalapenos in half length-wise and remove seeds (wear gloves if you have even the tiniest cut on your hand or are sensitive). Chop the jalapeno's fine.
In a large bowl combine softened cream cheese, cheddar cheese, sliced jalapenos and egg, mix well.
In a separate shallow bowl combine panko breadcrumbs, salt, garlic powder, and onion powder, mixing well.
Roll mixture into 1 inch balls, then roll each ball in the breadcrumbs. Place on lined baking sheets, one inch apart.
Bake in the preheated oven for 8 minutes, carefully turn (TIP: let them cool for a minute or two before you turn them!) and bake for 3-7 minutes more, or until both sides are lightly browned. WATCH CAREFULLY!
Remove from the oven and cool for a minute or two before serving.